IgG4 plasma cells in inflammatory myofibroblastic tumor: inflammatory marker or pathogenic link?
نویسندگان
چکیده
منابع مشابه
Malignant Inflammatory Myofibroblastic Tumor of the Lung with IgG4-Positive Plasma Cells
Inflammatory myofibroblastic tumor (IMT) is a rare lesion, described in numerous organ systems. The morphologic diagnosis relies on the presence of a fascicular arrangement of myofibroblasts with admixed lymphoplasmacytic infiltrate and slit-like vessels. We report a case of malignant IMT of the lung with rapid progression and features of IgG4-related disease in a 20 year-old woman. The patient...
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BACKGROUND Inflammatory myofibroblastic tumor (IMT) is a neoplasm of unknown etiology occurring at various sites. By definition, it is composed of spindle cells (myofibroblasts) with variable inflammatory component, hence the name is IMT. CASE PRESENTATION The present case is of a 46 years old woman presented with a history of flank pain, abdominal mass and intermittent hematuria for last 6 m...
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A 28-year-old woman was referred to our hospital because of abdominal pain, weight loss and a palpable intra-abdominal mass. A CT scan revealed a tumor with a diameter of 7 cm with sharp margins, intra-tumoral fatty components and enhancing soft tissue. After initial workup, which suggested an inflammatory myofibroblastic tumor (IMT), she underwent laparotomy with complete resection. Pathologic...
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We report a case of a splenic inflammatory pseudotumor (myofibroblastic tumor) in a 43-year-old man with a 5-year history of chronic bronchitis and sleep apnea syndrome. The patient was hospitalized because of a screen-detected splenic mass lesion. His sputum cultures revealed Mycobacterium avium complexes on only one occasion. Imaging studies revealed a 7 cm solitary tumorous lesion, and diffe...
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Inflammatory myofibroblastic tumor (IMT) is an uncommon mesenchymal solid tumor commonly documented in children and young adults. Here, we report a case of IMT in colon confirmed pathologically after laparoscopic anterior resection. A 35-year-old man presented with anal bleeding after defecation for 2 weeks. Colonoscopy demonstrated a mass with shallow ulceration in the central area and irregul...
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ژورنال
عنوان ژورنال: Modern Pathology
سال: 2011
ISSN: 0893-3952,1530-0285
DOI: 10.1038/modpathol.2010.226